Scientific studies published in world-class journals
Beyond You is the result of more than 20 years of research in genetics and data science by top-level researchers from institutions such as the Hospital Sant Pau in Barcelona and the UPC.
The impact of sex on gene expression in human tissues
Data from the Genotype-Tissue Expression (GTEx) project were examined and found that 37% of genes in at least one of the 44 tissues studied exhibited tissue-specific and sex-biased gene expression. They also identified a sex-specific variation in the cellular composition of the tissues. In general, the effects of gender on gene expression were small, but genome-wide and mostly mediated by transcription factor binding.
Affected pathways and transcriptional regulators in the response of gene expression to an ultramarathon route
For the first time, we report the genome-wide GE profile in a group of 16 runners participating in an 82 km UMT competition. We quantify your differential GE profile before and after the race. We observed significant differences in the expression levels of 5084 protein-coding genes, resulting in a 14% overrepresentation of human biological pathways.
Evaluation of a personalized intervention based on transcriptomic analysis of blood samples from overweight and obese patients
Determine if it is possible to make personalized recommendations to patients with obesity or overweight based on their blood transcriptomic profile and evaluate the changes.
Analysis of the transcriptome in response to resistance exercise in non-elite marathon runners
Analyze the impact of marathon running on non-elite athletes by identifying which systems may be expressed differently during such activity. Blood samples were taken from non-elite athletes who participated in the Barcelona Marathon at three different times: before the marathon at baseline levels, immediately after completion, and 24 hours after completion.
Athletic performance: transcriptomics and external load monitoring in sports competition
Understand the impact of a handball practice in sub-elite athletes by recognizing the transcriptomic changes that occur throughout a match and determining the correlation between internal (gene expression) and external (EPTS variables) loads to measure acute responses and chronic exercise.