We have published a new study in collaboration with Barça Innovation Hub. Click here to read de paper.

#50 Uncovering the Causes of Cognitive Decline and the Road to Recovery


This case study delves into the journey of a 62-year-old individual experiencing a decline in cognitive function. Despite thorough medical evaluations, a definitive diagnosis remained elusive.


To leverage advanced blood testing, specifically a metabolic panel, to pinpoint underlying metabolic imbalances potentially contributing to the cognitive decline.

Challenges Encountered:

  • Memory Lapses: The patient reported frequent forgetfulness, impacting daily routines and causing significant distress.
  • Diminished Focus: Difficulty concentrating and staying on task hampered work efficiency and social interactions.
  • Executive Function Issues: Planning, organizing, and decision-making became increasingly challenging.

Metabolic Pathway Disruptions:

Analysis revealed irregularities in key pathways:

  • Neurotransmitter Synthesis: This pathway, crucial for brain communication, showed imbalances, potentially affecting cognitive function and mood.
  • Glucose Metabolism: Dysregulation here suggests inefficient energy utilization within the brain, impacting its overall performance.
  • Oxidative Stress Pathways: Imbalances indicate a diminished capacity to neutralize free radicals, which can damage brain cells.

Personalized Intervention Plan:

  • Neurotransmitter Support: Dietary modifications rich in B vitamins (found in poultry, fish, and legumes) and choline (present in eggs and liver) to promote healthy neurotransmitter production.
  • Enhanced Energy Supply: Introducing complex carbohydrates (whole grains) and healthy fats (avocados, nuts) to provide sustained energy for optimal brain function.
  • Combating Oxidative Stress: Supplements like Vitamin C and astaxanthin, a powerful antioxidant, to enhance cellular defenses against free radicals.

Recovery Strategy:

  • Dietary Adjustments: A personalized plan focusing on brain-healthy foods like leafy greens, berries, and fatty fish.
  • Physical Activity: Regular exercise, tailored to fitness level, to improve blood flow and oxygen delivery to the brain.
  • Stress Management Techniques: Practices like meditation and deep breathing to reduce stress hormones, which can negatively impact cognition.

Outcomes and Conclusion:

The patient experienced a significant improvement in memory function, focus, and overall cognitive performance. This case study highlights the effectiveness of metabolic profiling in uncovering the root causes of cognitive decline, paving the way for personalized and targeted interventions.

Follow us: